Predictors at Exhibitor Relations have said they expect the fourth instalment of the Marvel series to make an astonishing $282 million (£212m) on its opening weekend in the United States.
If they're right this would see it surpass the saga's previous movie, Avengers: Infinity War, which holds the current record for highest grossing film after raking in $258m on its opening weekend last year.
Speaking to Bloomberg, however, senior analyst Jeff Bock did say that it's not a certainty just yet.
He said: "The only thing that could really affect the opening weekend would be a running time that exceeded three hours, which has yet to be confirmed by Disney."
The new film is set to break all records set before it. Credit: Marvel
A three-hour film could mean fewer showing times at cinemas, resulting in less money for the studio.
But it's not just about the money for everyone - an entire theatre has been booked out for two fans battling cancer so they can enjoy a special screening of the film.
It's been organised by Dillon Hill and Clay Stevens, whose charity One List One Life tries to help people with cancer with completing their bucket lists.
Their latest good deed was inspired by a fan named Lexi, who was diagnosed with Ewing's Sarcoma in 2017 and given a 17 percent chance of surviving. Since then, the charity has helped her tick many things off her list, such as visiting Universal Studios, playing with a pile of puppies and swimming with dolphins.
Number four on her list is her dream of meeting 'any Marvel actor'. Now, obviously this was going to be trickier to arrange than a trip to Universal Studios, so Mr Hill and Mr Stevens had to think outside of the box.
By renting out an entire theatre at Studio Movie Grill in Rocklin, California, USA, the pair are hoping they will generate enough buzz online to catch the attention of Marvel.
The charity isn't necessarily expecting the gesture to secure a face-to-face meeting for Lexi, but they're hoping they may be able to arrange a video message to put a smile on her face - and all of the faces in the audience for that matter.
Speaking to ComicBook.com, the One List One Life team, said: "Our end goal for this event is to have a theatre full of people that have been greatly affected by cancer, including Lexi, then surprise them with a video from some of the cast and crew.
"We will be documenting it all, so hopefully we can bring some joy and surprises."
Are you listening, Marvel?
Avengers: Endgame is set to be released in the UK on 25 April.
Featured Image Credit: Marvel Studios