On this day in 2007, Kate and Gerry McCann returned to their apartment in Praia da Luz, Portugal to find that their daughter, Madeleine, had gone missing.
Since then the couple, from Leicester, have done all in their power to locate and find out what happened to the three-year-old.
So far, their search has not been successful, though there have been a handful of 'leads' in the case.
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Credit: Sky News
Tonight, BBC One aired a documentary on the youngster's disappearance called Madeleine McCann: 10 Years On.
People were quick to take to social media to air their views on the show.
Across Twitter, there was a mixture of emotions, with most people shocked at how quickly ten years has gone, as well as confusion over the whole case.
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Many viewers said that so many questions still remain about the missing child.
Others speculated whether or not Gerry and Kate McCann were in some way involved.
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The McCanns were named suspects on 7 September 2007.
Against advice from their lawyer, Gerry did respond to questions - but Kate declined.
After the gruelling interview, it wasn't until July 21 the next year that the Portuguese Attorney General Fernando Jose Pinto Monteiro closed the case, citing no evidence against the McCanns.
Since May 3, 2007, a worldwide search has been conducted.
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Some 40,000 documents have created thousands of enquiries and 600 pursued suspects.
There are so many unproven theories as to what happened: was it a burglary gone wrong? Was it a planned abduction? Did sexual assault have a part to play? Did Maddie's parents, Kate and Gerry, have anything to do with it?
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Last month Scotland Yard chief Mark Rowley said there are still 'critical' leads that are of 'great interest' in the investigation.
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The only four official suspects investigated by the Met Police over the abduction of Madeleine McCann have also been ruled out of the inquiry.
Asked if police were any closer to solving the case than they were six years ago, Mr Rowley said: "I know we have a significant line of inquiry which is worth pursuing, and because it's worth pursuing it could provide an answer, but until we've gone through it I won't know whether we are going to get there or not."
Credit: PA
He added that there was no 'definitive evidence' as to whether Madeleine was alive or dead and reaffirmed that 'there was no reason whatsoever' to suspect Madeleine's parents were involved in the disappearance.
"However she left that apartment, she's been abducted," he said.
"This is a young girl who is missing.
"We've got some thoughts on what we think the most likely explanations might be and we are pursuing those."
A few months ago, Operation Grange was given £85,000 of Home Office funding to extend its investigations until September.
Four detectives are currently working on the case in the UK and over £11 million has been spent on it in total.
Featured Image Credit: PA/TwitterTopics: Kate McCann
