Spurs' prolific Harry Kane was looking to snap a mini-goal drought after firing blanks against Huddersfield and Juventus.
But the visitors didn't get off to a great start in their match against Bournemouth after Junior Stanislas opened the scoring. Mauricio Pochettino's day then got a whole lot worse after Harry Kane suffered a knock to his ankle thanks to home keeper Asmir Begovic.
The star striker was subsequently forced off in the 34th minute with Erik Lamela entering the fray.
The Spurs boss has confirmed he's injured his right ankle, with initial reports suggesting ligament damage. He'll undergo a scan tomorrow to see just how bad the injury is.
"I hope it is not a big issue," said Pochettino.
"We need to wait because we will scan his ankle. He suffered an injury that is to the same ankle he suffered before. He is positive. Harry has a great character and is always positive. If you are positive you start the recovery from the injury from now."
Kane's right ankle has caused him grief before with the England footballer missing 14 games last season due to two separate bouts of ligament damage in September and March.
Of course he'll be hoping for a speedy recovery so that he doesn't leave the Spurs in the lurch, but also because he's still hoping to be the Premier League's top scorer. He's netted 24 goals this season, but so has Mo Salah.
Kane's issue wasn't even the only injury that plagued the Spurs during today's match, with forward Dele Alli suffering a groin niggle.
Thankfully though, Tottenham's boss doesn't think the injury will cause a 'big issue'.
While the Spurs had a double whammy of injuries, it didn't seem to affect the rest of the team as they beat Bournemouth 4-1, with Heung-min Son netting a brace, while Dele Alli and Serge Aurier also got on the score-sheet.
Pochettino said: "We played fantastic football. If you want to be competitive, if you want to arrive at the end of the season with some possibility to win something or to achieve the targets you have, you need to have a big squad and you need 24, 25 players with the same objective to fight for the team when the gaffer calls them."
The Spurs' next match isn't until April 1 against Chelsea, but Kane's injury will not only be a concern for Tottenham but for Gareth Southgate as well, with the World Cup only three months away.
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