Hanks, 65, has, of course, taken on a number of iconic roles in his time as an actor, having played everyone from the loveable, kind-hearted Forrest Gump in the 1994 film of the same name through to single dad Sam Baldwin in Nora Ephron's timeless romantic comedy Sleepless in Seattle.
But it turns out some of those bigger titles aren't the ones that the star holds closest to his heart, having spoken about his top three in a recent episode of The Bill Simmons Podcast.
Hanks explained that his criteria for what constitutes a 'favourite' film may differ from others', given that he will have a different relationship with each project after working so closely on it.
He said: "I would not [make the selection] according to the way the movies came out.
"I'd do it in the way of the personal experience I had while doing them."
He continued to name his 2012 sci-fi flick Cloud Atlas as one of his all-time top picks, saying that the film had been 'shot on a hope and a dream and nothing but a circle of love'.
The film itself received a fairly lukewarm reception from critics, but Hanks said shooting the movie was nothing short of 'magical'.
He recalled how it had been the first time he'd ever shot extensively in Germany, saying he felt he was surrounded by 'history'.
"But the work itself, we were part of this big, massive ensemble of fantastic people who were just trying to do the hardest, best work on a deep throw... that whole movie was such a deep throw that making it was magical," the actor added.
Hanks also spoke warmly about 1992's A League of Their Own, which he sees as another of his favourite films - again something that was down to the production rather than the end result.
Being a sports comedy-drama follows an All-American Girls Professional Baseball League, Hanks explained how working on the film allowed him to play baseball for an entire summer, not just when shooting but also during pre-production.
Finally, his third favourite movie may come as little surprise, as he picked Cast Away, the 2000 drama about a man stranded on a desert island after his plane crashes into the South Pacific.
"We just had bold adventures when making that movie," Hanks said.