ITV has axed The Jeremy Kyle Show after a guest on the show died of an overdose.
Steve Dymond, 63, failed a lie detector test on the popular daytime chat show and was found dead in a Portsmouth flat 10 days later.
The show was immediately pulled off air after Dymond's death while station bosses decided on its permanent future.
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That future has been decided and will see the end of the show, which has been a fixture of ITV daytime programming for 14 years.
The channel has decided to scrap the programme following a backlash from both Dymond's family and an outraged public.
ITV CEO Carolyn McCall said: "Given the gravity of recent events we have decided to end production of The Jeremy Kyle Show.
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"The Jeremy Kyle Show has had a loyal audience and has been made by a dedicated production team for 14 years, but now is the right time for the show to end.
"Everyone at ITV's thoughts and sympathies are with the family and friends of Steve Dymond.
"The previously announced review of the episode of the show is under way and will continue.
"ITV will continue to work with Jeremy Kyle on other projects."
Dymond went onto the show to prove that he had not been unfaithful to his girlfriend, Jane Callaghan.
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Despite protesting his innocence, Dymond, from Gosport in Hampshire, failed a lie detector test and the pair separated immediately after the episode was filmed.
After his death, Callaghan told The Sun that she thought he had taken a fatal overdose of arthritis medication.
She said: "He wanted to go on. He was really excited and confident. But it was all a front and I knew it. He wasn't well at all."
Jane added: "He was still my fiance. I still loved him. As much as he was a pig to me I still loved him."
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Dymond's son, Carl, added: "He told me, 'Kyle really laid into me'.
"Presumably that was at the point when they announced the lie detector result. I'm satisfied he intended to kill himself."
Dymond's death is to be the subject of an inquest that will be opened within the next few days. A spokesperson for the Portsmouth coroner's office told the BBC that it was currently awaiting the results of a post-mortem investigation.
After the show was taken off air, a statement made by ITV read: "Everyone at ITV and The Jeremy Kyle Show is shocked and saddened at the news of the death of a participant in the show a week after the recording of the episode they featured in and our thoughts are with their family and friends.
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"ITV will not screen the episode in which they featured.
"Given the seriousness of this event, ITV has also decided to suspend both filming and broadcasting of The Jeremy Kyle Show with immediate effect in order to give it time to conduct a review of this episode of the show."
Topics: UK News, TV and Film, UK Entertainment, Jeremy Kyle