Jeremy Clarkson shared the major difference changing from Ozempic to Mounjaro made in his life

Jeremy Clarkson has opened up about the difference he noticed since switching from Ozempic to Mounjaro for weight loss.

An ex-user of Type-2 diabetes drug Ozempic, which did nothing for his sweet snack-loving disposition, the Clarkson's Farm presenter has spoken of the major difference between the two products in an interview with The Times.

The 65-year-old underwent emergency heart surgery towards the back end of 2024, having been just 'days away from death', and in an extra effort to change his lifestyle and shed some poundage, he revealed he had turned to Ozempic.

But Clarkson has been candid about how the Type-2 diabetes medication did not agree with him and made him 'sick'.

Writing about his frustrating Ozempic journey - which he admitted he began two years ago - he wrote in his column for The Times: "My body lost the ability to deal with gluttony but once the initial enthusiasm had worn off, my mind still wanted to breakfast on Cadbury Fruit & Nut.

"This meant I was sick a lot."

Ozempic has been a popular avenue amongst celebrities wanting to shed the pounds, despite the drug not being approved for weight loss (Steve Christo - Corbis/Corbis via Getty Images)

Jeremy Clarkson's experience with Mounjaro after Ozempic

But in more recent times, the former Top Gear host has switched to Mounjaro for weight loss instead - which is officially approved in the UK for such treatment, unlike Ozempic.

Clarkson said in his interview with The Times of his Mounjaro experience: "I could open the fridge door, look at all the goodies, then close it.

"You can pop a teaspoon of snail caviar — made from unborn snails — on to half a Ritz cracker and you have yourself the 21st century's answer to a medieval banquet."

That's a considerable behavioural progression for someone who caved in and put on half a stone after taking Ozempic for six months.

Despite Mounjaro running out as the clear favourite of the two, Clarkson has lamented no longer being able to enjoy the full splendour of foods on offer to him.

"You find yourself living a minibar existence," he reflected, joking that a 'handful of sunflower seeds' is enough to keep his appetite satiated. "That’s not living. That's existing."

Jeremy Clarkson has transitioned onto Mounjaro after using Ozempic (Jeff Spicer/Getty Images)

What is the difference between Ozempic and Mounjaro?

Administered subcutaneously, both injections - known as 'incretin mimetics' - are primarily used by Type-2 diabetes patients to control their blood sugar.

However, as a recent adoptee by the weight loss community, Mounjaro has proven significantly more effective in that regard as it works on two hormone receptors, GLP-1 and GIP, compared to Ozempic's sole focus on the former, via Click2Pharmacy.

Ozempic is also approved to reduce the risk of cardiovascular issues, which isn't the case for Mounjaro, while their doses are much different too.

Mounjaro's weight loss dose is a maximum of 15mg and Ozempic's is 2g.