Grim searches prosecutors say alleged killer made before he 'poisoned wife's protein shakes'

Warning: This article contains discussion of suicide which some readers may find distressing.

A US dentist accused of poisoning his wife's protein shakes has had some of his disturbing internet searches revealed in court.

James Craig, a 47-year-old from Denver, Colorado, will take to the stand next week, two years after his wife Angela died - with toxicology tests taken after her death finding she had been poisoned with cyanide and tetrahydrozoline.

Prosecutors are now claiming that her husband was the man behind her mystery symptoms, and think that an argument the two had shortly before her death, as well as his online searches, could be the key to proving that he was the man behind it.

James' trial will begin on Monday next week (14 July), where he faces charges including first-degree murder, solicitation to commit murder and solicitation to commit perjury. He has pleaded not guilty on all charges.

James Craig is facing a number of charges in connection with his wife's death (Aurora Police Department)

The married couple's argument in their home saw Angela confront James about allegedly hinting to hospital staff that his wife was suicidal.

It is believed that jurors will be shown the footage of them arguing in the kitchen, where Angela asks: "It’s your fault they treated me like I was a suicide risk, like I did it to myself, and like nothing I said could be believed."

The judge approved the video, as prosecutors believe it could be vital in proving that the mother-of-six did not kill herself.

James allegedly purchased arsenic online at the time his wife was experiencing unexplained symptoms, including headaches and dizziness.

Prosecutors claim that he also searched for answers to questions including ‘how to make murder look like a heart attack’ and ‘is arsenic detectable in an autopsy?'

Craig's suspect searches and orders could be key in the jury's verdict (Facebook)

A colleague at James' practice also discovered a shipment of potassium cyanide, something he alleged was for surgical purposes.

The couple had been married for 23 years and had six children together, but police believe he had recently started a new relationship with a fellow dentist and was trying to start a new life following financial troubles.

An investigation was initially launched when Craig’s business partner, Ryan Redfearn, told a nurse treating Angela that he was concerned she could have been poisoned with the cyanide, with the nurse then passing this on to police.

The news comes shortly after Australian woman Erin Patterson was found guilty of murdering her estranged husband's family by deliberately serving them poisonous mushrooms.

Last year, a family in Brazil were also left devastated after three people died when a Christmas cake was found to contain poison.

James' trial will begin on Monday, 14 July.