
An Amazon cargo plane has crashed after it overshot the runway at Miami International Airport in Florida and 'struck multiple vehicles'.
Footage shared online shows plumes of smoke billowing from the plane, which has the Amazon arrow logo across the tail.
The Boeing 767-300 cargo plane had arrived from San Juan, Puerto Rico on Sunday (6 September) afternoon.
It is unclear how many people were onboard the flight.
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The airport has implemented an air and ground stop, preventing all other flights from landing or taking-off.
In a statement the airport said: "At approximately 2 p.m. today, Prime Air flight 7598 overran Miami International Airport’s diagonal runway and is disabled at the northwest end of the airport.
"All runways and taxiways at [Miami International Airport] are currently closed as of 3:00 p.m. and a ground stop is in effect."
Miami-Dade Fire Rescue is responding to the scene, the airport says, directing ‘questions regarding injuries or fatalities’ to them.
As yet, details on casualties are unclear but first-responders are at the scene treating 'multiple' patients.

Miami-Dade Fire Rescue said in a statement: "Over 60 Miami-Dade Fire Rescue units are on scene of an incident involving a plane that overran a runway and struck multiple vehicles near Miami International Airport.
"Units arrived to find an airplane that had caught on fire as a result of this crash, with heavy flames and smoke showing. Firefighters are working on extinguishing the fire and assessing patients."
The statement continued to say there are ‘multiple patients’ and added: “We will provide additional updates on patients as they become available.”
Amazon spokesperson Kelly Nantel told NBC News that the cargo plane was being operated by 21 Air.
Nantel said: “This is a fast-moving situation and we’re still gathering details. We’re working closely with local authorities and officials to understand exactly what happened.
“Right now, our absolute priority is the safety, well-being, and care of everyone involved.”
Miami-Dade County mayor Danielle Levine Cava said in a statement on X her office was carefully ‘monitoring’ the situation.
She wrote: “We are closely monitoring the situation at @iflymia following this afternoon’s incident involving a Prime Air cargo aircraft. @MiamiDadeFire and our airport teams are on the scene.
“Right now, our focus is on everyone involved and making sure our first responders have what they need. We will provide updates as we learn more.”
Images from the scene show the Amazon cargo plane tilted downwards with what looks to be soot smeared along the side of the cabin.
The Miami-Dade Sheriff's Office said: "Due to a major first responder presence, NW 67th Avenue between NW 25th Street - NW 36th Street is currently closed. Expect delays and seek alternate routes.
"Flights at Miami International Airport are also currently grounded. Travellers should expect delays."
US transportation secretary Sean Duffy said on X that responders would 'assess the scene after an Amazon cargo plane overran the runway'.
The Federal Aviation Authority (FAA) has confirmed the incident and said in a statement that it was investigating the matter.