Jake Paul and Mike Tyson are set to exchange blows in a heavyweight boxing match viewed by millions around the world tonight, live on Netflix.
But there will be strict rules both fighters have to follow when it comes to the fight being a fully sanctioned, professional bout.
Taking place in Arlington, Texas, the two boxers will make millions when they finally fight at the home of the Dallas Cowboys with more than 70,000 spectators expected to turn up and take their seats, with a number of famous faces to gather around ringside.
Tensions have risen in the build up to the fight, with Tyson slapping Paul at their weigh-in and final face-to-face encounter last night (14 November).
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Taking to the ring at 10pm CT on Friday (15 November), the ring walks for both fighters will be at roughly 4am GMT on Saturday (16 November) for UK viewers. The undercard will begin around three hours before this.
As part of the regulations set out by the Texas Department of Licensing and Regulation, Tyson has already had to pass a brain test (EEG) and a heart test (EKG) before being allowed to step inside the ring.
And the regulations don't stop there, with Paul explaining specific drug testing rules that are in place for the fight.
Paul recently made an appearance on the Suga Sean O'Malley podcast, where he clarified the drug-test rules for the fight.
O'Malley's coach, Tim Welch, said: "They've got to let Mike use some special supplements, a little bit. I mean 58-years-old.
"Having the lifestyle that he's had, his natural testosterone can't be that high, so hopefully he's able to get boosted up a little bit."
Replying to the testosterone comments Paul said: "Well, there's like a big, panel, drugs test from the Texas State Commission."
Tyson has openly admitted to his recreational drug use, with him being an avid user of psychedelic substances. In August, he even said he 'always trains on mushrooms', in reference to his consumption of magic mushrooms.
Making the comment on Logan Paul's Impaulsive podcast, he said consuming them 'makes him feel beautiful'.
"They take me to heaven, baby," he said.
Paul has had to come out and deny that he uses performance enhancing drugs after meritless steroid accusations were put his way.
"First of all, obviously none of that is true," Paul said on a podcast ahead of one of his fights, even publishing his own negative drugs tests to prove he is clean.
Under Texas Department of Licensing and Regulation rules, boxers cannot be under the influence of any drugs, unless prescribed by your doctor.
Boxers cannot engage in the manufacture, sale, distribution, use, or possession of illegal drugs at any time.
And the drugs for which tests are required under the regulations are marijuana, cocaine, amphetamines, phencyclidine (PCP), and opiates.
Jake Paul is the favourite to win the fight with bookmakers, coming in at 13/18 while Tyson is priced at 2/1. The draw is currently even.
Topics: Boxing, Drugs, Jake Paul, Mike Tyson, Netflix, Podcast, Sport, YouTube
Tom Earnshaw