A clip from the comedian's appearance on the Two Shot podcast appeared on TikTok this week, focusing on one of his iconic philosophical rants - just like the ones he was made famous by in his chats with Ricky Gervais and Stephen Merchant.
In the footage, host Craig Parkinson turns the topic of conversation to changing tastes, something Karl evidently feels passionate about.
"I've changed I think over the years, because of the different jobs, you're constantly changing," he says.
Karl then discusses the idea that every seven years our cells regenerate, adding: "You're like a different person because your cells are changing. That's why a lot of relationships end after seven years, because you're kind of a different person if that makes sense."
In the context of his career, the Ricky Gervais Show legend explains that whenever he takes on new ventures such as An Idiot Abroad, people still demand he goes back to what he was doing years ago.
"Here's me trying to do something different but people are like, 'I prefer that. Do more of that.' And it's like, I'm not that."
He later goes on to say: "It's like they look at me like I'm Homer Simpson or something, that is this thing that doesn't age.
"If Homer was real, he'd probably be alright by now. Do you know what I mean? The kids would've grown up, he'd have a different life with Marge, his brain would've changed. He's changed as a person.
"But he doesn't change in the Springfield world because he's a cartoon. And I think people look at me like that."
In true Karl fashion, he finishes the rant with a hint of irritation in his voice, reiterating that people always badger him to return to what he was doing 10 years ago.
"I don't know what you were like 10 years ago, but I'd hope you've changed a bit."
Plenty of people found his speech hilarious, with one writing: "The Simpsons analogy proves he hasn't changed as much as he thinks he has."
"His Homer Simpson analogy is spot on," said another, while a third wrote, "The Homer analogy is actually genius."
Featured Image Credit: Sky One