ladbible homepage
ladbible homepage
  • Home
  • News
    • UK
    • US
    • World
    • Ireland
    • Australia
    • Science
    • Crime
    • Weather
  • Entertainment
    • Celebrity
    • TV
    • Film
    • Music
    • Gaming
    • Netflix
    • Disney
  • Sport
  • Technology
  • Travel
  • Lifestyle
  • Money
  • Originals
    • FFS PRODUCTIONS
    • Say Maaate to a Mate
    • Daily Ladness
    • UOKM8?
    • FreeToBe
    • Citizen Reef
  • Videos
  • Advertise
  • Terms
  • Privacy & Cookies
  • License Our Content
  • About Us & Contact
  • Jobs
  • Latest
  • Archive
  • Topics A-Z
  • Authors
Facebook
Instagram
X
Threads
Snapchat
TikTok
YouTube
Submit Your Content Here
  • GAMINGbible
  • LADbible Group
  • UNILAD
  • SPORTbible
  • Tyla
  • FOODbible
  • UNILAD Tech
Woman used ‘micro-dosing’ method to quit weight loss jabs after losing 2st in 4 months
Home>News>Health
Published 09:46 6 Aug 2025 GMT+1

Woman used ‘micro-dosing’ method to quit weight loss jabs after losing 2st in 4 months

Mum-of-two Madison Shari, 33, was able to wean herself off tirzepatide

Anish Vij

Anish Vij

google discoverFollow us on Google Discover

A woman who lost over two stone in just four months has revealed how she was able to quit weight-loss jabs for good by 'micro-dosing'.

Madison Shari, 33, was struggling to keep her food down after giving birth to her two daughters, now aged three and five.

The Missouri resident told LADbible that 'it became about survival' and that she would 'eat whatever was convenient' to keep going.

But by trying to balance her PR and marketing job with raising two kids, before she knew it, she became 'clinically overweight' at 170lbs (12st).

Advert

After making the decision to use compound tirzepatide (the active ingredient in Mounjaro), Madison lost over 2st in just four months, and by the six-month mark, she lost a total of 2.5st.

Madison Shari weaned herself off tirzepatide in six months (YouTube/Madison Shari)
Madison Shari weaned herself off tirzepatide in six months (YouTube/Madison Shari)

Now, the thought process for most people who use weight loss jabs is that 'I don't want to be on it forever'.

Quitting cold turkey, however, brings all sorts of challenges and side effects that can lead to putting all of the weight back on.

The content creator, instead, was able to wean herself off it during a six-month micro-dosing period and has been able to maintain her weight of 9.5st for nearly a year since.

What is 'micro-dosing' from tirzepatide?

Micro-dosing involves taking very small amounts of medication, often lower than the standard prescribed amount. This can either be a less frequent dose or a reduced dose of, in this case, tirzepatide.

The mum said she became 'clinically overweight' which wasn't good for her heart condition (Supplied)
The mum said she became 'clinically overweight' which wasn't good for her heart condition (Supplied)

And because the mum-of-two suffers with a heart issue, she was prescribed with the active Mounjaro ingredient under medical supervision.

For the first four months, she took the 'lowest standard dose' for active weight loss, and then for the last two months, she started micro-dosing at 1.5mg (below standard dosing).

"I did the lowest standard dose during my first four months when I was actively losing weight, and then my last two months on it... I did 1.5, which would be considered a micro-dose.

"I have been off it almost a year now, and I have not gained any of the weight back. Now, everyone's body is different. Some people are going to need to be long-termers on it, definitely."

Madison has been able to maintain her weight for nearly a year after coming off weight loss jabs (Supplied)
Madison has been able to maintain her weight for nearly a year after coming off weight loss jabs (Supplied)

Fewer side effects

Micro-dosing can cause fewer side effects, as Madison explains: "It's also really nice as you wean off of it, or prepare to get off of it, you're not like, shocked by the hunger coming back. It comes back slower if you wean off of it or micro-dose for a while.

"I definitely had less side effects when I was on my micro-dose and when I was weaning off of it."

How Madison was able to keep the weight off

It is advised while using any weight-loss drug to continue to eat healthy, exercise regularly and to live a balanced lifestyle, which was exactly Madison did - and is still doing.

The content creator shares wellness and health videos on social media (YouTube/Madison Shari)
The content creator shares wellness and health videos on social media (YouTube/Madison Shari)

High protein, low carb diet

"Now that I'm eating more protein and fibre, less carbs, my body does just feel overall healthier," she says.

"When I was on the medicine, I made sure my minimum was 1200 calories. Now I would say, on an average day, I eat between 1600-1800 calories."

Strength training

“I was very cardio focused, and when I switched to strength training two or three days a week, I noticed a big difference," Madison added.

"When it comes to actually improving your metabolism and building strength and improving your body's function, I think strength training is something that you need to keep in mind and not forget."

Intermittent fasting

Madison says she tries to give herself a 14 to 16 hour break from eating food 'which is great for insulin resistance, digestion, breaking down fat, all of that'.

Side effects from tirzepatide

"I did have some nausea and some fatigue, I think were my biggest complaints, maybe occasional stomach upsets," she admitted.

"Sometimes uncomfortable, but it didn't interfere with daily life in the sense that I ever felt like I had to stay home from work or anything."

Featured Image Credit: Supplied

Topics: Mounjaro, Health, US News

Anish Vij
Anish Vij

Anish is a Journalist at LADbible Group and is a GG2 Young Journalist of the Year 2025. He has a Master's degree in Multimedia Journalism and a Bachelor's degree in International Business Management. Apart from that, his life revolves around the ‘Four F’s’ - family, friends, football and food. Email: [email protected]

X

@Anish_Vij

Recommended reads

Doctor explains true effects of 'Carrotmaxxing' trend people are doing to 'tan themselves'Getty Stock ImagesEmotional message behind semi-colon tattoo and four others you didn't know the meaning ofThe Washington Post/GettyDoctor issues serious warning over 'most powerful weight loss jab ever' that outperforms Mounjaro and WeGovyGetty StockDeath row inmate's execution called off after botched attempt to take his lifeTennessee Department of Correction

Advert

Choose your content:

6 hours ago
7 hours ago
  • The Washington Post/Getty
    6 hours ago

    Emotional message behind semi-colon tattoo and four others you didn't know the meaning of

    The tattoo has a particular meaning for some people

    News
  • Tennessee Department of Correction
    6 hours ago

    Death row inmate's execution called off after botched attempt to take his life

    Even Kim Kardashian has had her say...

    News
  • Photo by Roy Rochlin/Getty Images
    7 hours ago

    Singer Jack Avery speaks out after child's mother arrested in alleged plot to murder him

    Influencer Gabriela Gonzalez, 24, is accused of trying to hire a hitman on the dark web over a custody dispute

    News
  • Getty Stock
    7 hours ago

    Doctors explain whether you should megadose on creatine as side effects revealed

    The supplement is popular among people as part of their workout regimen

    News
  • Groundbreaking study finds rapid weight loss is better than gradually losing weight
  • New study finds weight loss jabs could halve the number of sick days people take off work
  • Doctor weighs in on true impact of weight loss jabs after one month
  • Doctor explains unexpected trend of people gaining weight while on weight loss jabs