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A lot of us probably couldn't get away with lighting up before work, but the Hollywood actor, screenwriter, director and producer reckons it gets his head in the right space to do his job.
He explained to The Irish Times how weed actually helps him throughout the day and not just during the morning.
"I drink my coffee as I smoke my joint, and I continue smoking weed until I go to sleep," he said. "I often will wake up in the middle of the night and have a few hits of a joint if I'm not sleeping well."
He also elaborated on what it has been like being one of the most famous men in Tinseltown, explaining people don't often recognise him.
He said: "Before the pandemic, I would wander around LA aimlessly without anyone taking pictures of me for months and months and months on end."
Many people reckon he's a guy who looks like Seth Rogen, however he still gets a little uncomfortable when interacting with fans.
"Wearing a mask and everything, and someone recognised me," he said. "It was shocking to me. It just hasn't happened to me in so long.
"And if the person who did that is reading this, I'd like to apologise for my reaction. I maybe physically ran away from them."
While some people might criticise Rogen for promoting his weed use so liberally, he hasn't shied away from explaining its health benefits for him and his family.
In an interview with the New York Times, which was published on 4/20, Seth and his dad Mark spoke out about the drug and how useful it was for his teenage son.
Speaking to the publication, Mark said: "We had him on a strict diet that helped keep him in balance, but it wasn't 100 percent. Marijuana finally made his cells relax."
The Pineapple Express actor added: "It's just a tool we use to make our experience more palatable, and some people need those tools a lot more than others."
He added: "For me, it's like shoes. For you, it might be like sunglasses. Not everyone's the same. If someone doesn't need to smoke weed? Great. It's the same as someone telling me they don't wear glasses.
"Mazel tov! You don't wear glasses. I do!"
The 39-year-old actor, comedian and writer is famously fond of the drug has even started his own weed company, Houseplant.
The company, based in Toronto, offers different strain of dried flower cannabis, softgel capsules and pre-rolled joints in stores across Canada.
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