Known by pretty much everyone for guest starring as Rachel Green's sister in Friends, Christina Applegate is a cherished household face and name.
So, it's no surprise that everyone was on their feet as she appeared in front of hundreds at the 75th Emmy Awards.
The award-winning actress, known in recent years for her brilliant role in Netflix's Dead To Me opposite Linda Cardellini, had everyone on their feet after speaking candidly about her health problems.
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Applegate took to the stage alongside host Anthony Anderson to present the first award of the night, for the category of Best Supporting Actress in a Comedy.
The gong went to Ayo Edebiri for her role in The Bear, but the star of the segment was Christina herself.
She appeared with a cane, some two years after first being diagnosed with multiple sclerosis (MS).
The entire audience took to their feet, with 52-year-old Applegate even cracking a joke about them making fun of her MS by so easily getting our of their seats.
She also quipped: "We don't have to applaud every time I do something."
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The moment reduced the Hollywood star to tears.
In 2021, Applegate revealed her MS diagnosis on X, formerly known as Twitter.
She said: “It's been a strange journey. But I have been so supported by people that I know who also have this condition."
According to the NHS, MS is a condition that can affect the brain and spinal cord, causing a wide range of potential symptoms.
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This includes problems with vision, arm or leg movement, sensation or balance.
Sadly, it is a lifelong condition and cannot be cured. For some, it causes serious disability.
The NHS says: "It's most commonly diagnosed in people in their 20s, 30s and 40s although it can develop at any age.
"It's about two to three times more common in women than men.
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"MS is one of the most common causes of disability in younger adults."
Main symptoms include:
- fatigue
- difficulty walking
- vision problems, such as blurred vision
- problems controlling the bladder
- numbness or tingling in different parts of the body
- muscle stiffness and spasms
- problems with balance and co-ordination
- problems with thinking, learning and planning
Topics: Celebrity, Health, NHS, TV and Film, US News, Christina Applegate
Tom Earnshaw