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Signs and symptoms of oral sex-related throat cancer that can appear decades later

Home> News> Health

Updated 16:28 13 Mar 2026 GMTPublished 12:28 12 Mar 2026 GMT

Signs and symptoms of oral sex-related throat cancer that can appear decades later

Experts have revealed that symptoms can take as long as 20 or 30 years to show

Joshua Nair

Joshua Nair

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Cases of human papilloma virus (HPV) have increased among a certain age group, in spite of prior knowledge on the condition.

The health condition can cause throat or oropharyngeal cancer in high-risk cases, though many of the symptoms which indicate this can take years to show.

One of the most well-known causes of this type of cancer is oral sex, as actor Michael Douglas has shared that this was the cause of his stage IV squamous cell carcinoma oral cancer.

The Fatal Attraction actor revealed the diagnosis in 2010, but only revealed that it was caused by HPV three years later, adding that he could remember his doctor's face when a 'walnut-size tumour' was found at the base of his tongue.

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Now cancer-free, Douglas' case is often used as a cautionary tale as experts have explained the main signs and symptoms that you should look out for to identify HPV and stop it from progressing to something more serious.

Persistent neck pain can be a sign of throat cancer (Getty Stock Images)
Persistent neck pain can be a sign of throat cancer (Getty Stock Images)

Symptoms of throat cancer

According to UCI health, these are the common signs you should be looking out for:


  • A thickening in the cheek
  • A lump on the lip, mouth, neck or throat
  • A mouth or lip sore that isn't healing
  • A red or white patch found on the gums, tongue, tonsil or mouth lining
  • A hoarseness or change in voice
  • A persistent sore throat or a feeling that something is stick in your throat
  • A numbness of mouth or tongue
  • Pain in the jaw or ear
  • Pain or bleeding in the mouth
  • Difficulty chewing or swallowing
  • Chronic bad breath

Less commonly, the NHS reports that you can also experience fatigue or unintentional weight loss.

There are 2,000 new cases of laryngeal (throat) cancer every year in the UK, with instances more common in men over 60.

More young men have been diagnosed with throat cancer in recent years (Getty Stock Image)
More young men have been diagnosed with throat cancer in recent years (Getty Stock Image)

What have experts said of the rise in throat cancer cases?

It's been reported that the early detection and vaccination for HPV has led to a drop in cervical cancer in US women, but HPV-associated cancer of the tonsils, throat or back of the tongue have skyrocketed in men over the preceding three decades.

Dr. Tjoson Tjoa, a UCI Health otolaryngologist and surgeon who is a head and neck cancer specialist, explained: “What we’re seeing over the last five to 10 years is that the most common head and neck cancer is HPV-related oropharyngeal cancer.”

It was widely believed that men in their 70s and 80s with a history of drinking and smoking were more likely to have oropharyngeal caners, but from 1988 to 2004, it was found that cases in younger men without a history of longtime smoking or drinking had increased by three times.

Dr. Tjoar further highlighted: “In recent years, this practice has become more prevalent in developed areas of the world,

“HPV is the most common sexually transmitted disease, so much so that nearly all sexually active men and women are exposed to it.”

A new study has found that having over 10 sexual partners can increase the risk of developing throat cancer, with US researchers finding that among over 500 people, people with more sexual partners were more at risk of developing oropharyngeal cancer.

Those with over 10 sexual partners were 4.3 times more likely to develop mouth and throat cancers linked to HPV, while Dr Virginia Drake, study author and otolaryngologist at the John Hopkins University, spoke of how lifestyle habits also play a part.

163 of those polled had HPV-related oropharyngeal cancer.

Your chances of developing throat cancer increases with the number of sexual partners you have (Getty Stock Image)
Your chances of developing throat cancer increases with the number of sexual partners you have (Getty Stock Image)

Which signs can appear decades after exposure?

Many people can get a throat infection from the virus which eventually goes away, but there is the probability that they develop cancer in the throat, tonsils, or tongue.

This can take 20 to 30 years after exposure, in certain cases.

A vaccine to fight HPV was introduced in the US back in 2006, with it being recommended that children take the shot at 11 or 12-years-old, before they become sexually active.

Dr Tjoa explained that people are not making enough of a connection between HPV and throat cancers which were appearing in men and women, decades after being exposed.

The health expert that it is 'potentially completely preventable with vaccination', further claiming: “If 100% of boys were vaccinated before they became sexually active, we wouldn’t have this disease.”

Featured Image Credit: Getty Stock Image

Topics: Health, Cancer

Joshua Nair
Joshua Nair

Joshua Nair is a journalist at LADbible. Born in Malaysia and raised in Dubai, he has always been interested in writing about a range of subjects, from sports to trending pop culture news. After graduating from Oxford Brookes University with a BA in Media, Journalism and Publishing, he got a job freelance writing for SPORTbible while working in marketing before landing a full-time role at LADbible. Unfortunately, he's unhealthily obsessed with Manchester United, which takes its toll on his mental and physical health. Daily.

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@joshnair10

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