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The 59-year-old actor shared his latest creation with his 18.9 million Twitter followers and, despite it receiving over 33,000 likes, some people thought it was pretty distasteful and sexist.
Defending the former First Lady, one person replied to the tweet, saying: "Absolutely appalling to attack the first lady who did her job with grace and dignity and got nothing but criticism from everyone on the left.
"And it's shameful that not one woman from the left defended another woman for these baseless attacks."
Another added: "I always thought you were cool. Now you're too vindictive with pics like this.
"Why do the left target people with such venom in the exact way they preach against when the demonising others for doing it?
"This would be found sexist and anti female etc. Such hypocrisy!"
A third wrote: "Wow, that's low. I really liked you and I thought you were inspiring."
Unsurprisingly, there were many people more than willing to jump to the Ace Ventura actor's defence.
One wrote: "He is an actor/comedian that portrays men and women and makes people laugh. Which means no one is safe from being made fun of.
"Why are people acting hurt and surprised? Why so serious?"
Another added: "LOVE this!! And YOU!! Keep expressing yourself through your art!! If she wanted to be pictured in a better light, she should have performed better in the spotlight! Just saying!"
Despite the messages defending the 50-year-old wife of Donald Trump, Melania was voted the most unpopular First Lady in history after leaving the White House for the final time last week.
According to the latest CNN/SSRS poll, Melania's favourable rating was at 42 percent, while unfavourable was polling at 47 percent.
To put that into perspective, the average final popularity rating before Melania was 71 percent, with an unpopularity rating of 21 percent.
Hillary Clinton, who ended her term at 52 percent favourable and 39 percent unfavourable, was previously the lowest-rated First Lady.
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