Right, for starters - and this shouldn't need saying - don't try this at home, even if you do have a giant snake to hand.
It's not going to end well, as the video illustrates.
However, 'in the name of science' Aussie presenter Adam Thorn decided to let the snake have a free shot at him. It's fair to say that it looks pretty sore.
This whole sordid experiment took place on a History show called Kings of Pain.
Dunno, it looks pretty scientific to me.
Wearing a protective mask and a covering for his groin - naturally - he let out a scream of agony when the reptile sank its fangs deep into his arm tissue.
What is interesting is the slow motion footage of the incident. It revealed that the snake attacks first with the lower jaw before dislocating the upper jaw in order to land the blow with its considerable fangs.
As you might imagine, Adam was pretty shaken up. He screamed 'get off, get off," as his co-host, Rob 'Caveman' Alleva tried to pull the snake off him.
Then, Adam continued: "I've got a fang, I've got a fang hanging out of me."
He eventually needed stitches on the wound.
Incidentally, Rob didn't exactly get away scot-free. He was also bitten and needed to have two blood clots squeezed out of his arm.
These two clots - and no, we're no longer talking about the medical term - are the stars of this show for a reason.
Thorn, a wildlife biologist, and Alleva, a professional animal handler, have volunteered themselves to travel the world in order to get bitten by all manner of creepy crawlies and dangerous animals.
The pair have devised a 30-point scale to catalogue the amount of pain they experience. Honestly, the scientific rigour on show is off the charts.
They measure the duration, intensity, and damage caused by all of the bites in order to show animals the animals that they really don't want to get bitten by.
Of course, the real answer is any animal. You don't want to get bitten by any animal or insect if at all avoidable.
They're joined on this epic educational journey by Dr Justin Schmidt.
Schmidt did a similar experiment in the 80s when he developed a scale for insect sting pain.
Luckily, the reticulated python used on this episode is not venomous. However, it is a popular pet and can kill by constriction.
Other animals featured on the show include a tarantula hawk wasp, a giant Asian centipede, a lion fish, a fire urchin, and a Nile monitor lizard.
Featured Image Credit: History/Kings of Pain
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