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The trio have travelled - and argued - all over the globe for their hugely popular series, having brought their bromance to America, France, Italy and more so far.
In Gordon, Gino & Fred Go Greek, the stars will be heading out to Greece to check out the country's capital city of Athens and its many stunning islands - including Crete, the largest, which is where their journey will begin.
They will then move on in their RV to the likes of Santorini, Mykonos and Meteora, breaking up the driving with jet ski racing, shipwreck diving and fresh lobster.
ITV announced the show as part of its autumn programming, saying: "This time their RV is hitting the beautiful Greek islands and historical city of Athens, for a big fat Greek adventure, together again behind the wheel on an epic odyssey like no other.
"From island hopping on a catamaran, to jet ski racing and shipwreck diving, there will be bromance and bickering in equal measure.
"Thanks to an abundance of fantastic food, including the freshest lobster, chefs Gordon and Gino will be looking to prove that Greece's culinary credentials are up there with the very best of Europe.
"The guys will begin their adventure in Crete, Greece's largest island, before navigating their way to stunning Santorini, making their way to the party island of Mykonos and finishing their trip in the Greek capital Athens and the monasteries of Meteora.
"Travelling together in the birthplace of civilisation, what could possibly go wrong...?"
Meanwhile, ITV's drama highlights include Stephen, a three part sequel to The Murder of Stephen Lawrence starring Hugh Quarshie, Sharlene Whyte and Steve Coogan.
Martin Clunes returns in Manhunt, where he reprises his role as the former London Metropolitan Police Detective Chief Inspector Colin Sutton. This brand new four-part drama is the 'real-life story of the police pursuit of a notorious burglar and rapist, whose 17 year reign of terror left thousands of elderly people in South East London living in fear and is based on the diaries of Colin Sutton'.
Homeland writer and executive producer Patrick Harbinson has also adapted The Tower for ITV, based on Kate London's best-selling novel Post Mortem and starring Gemma Whelan, Emmett. J Scanlan, Tahirah Sharif and Jimmy Akimbola.
Angela Black is a Hitchcockian thriller starring Joanne Froggatt, Michiel Huisman and Samuel Adewunmi, which follows one woman as she 'risks everything she holds dear to fight back against the man who has suppressed and tormented her for most of her adult life', while Anna Maxwell Martin and Rachael Stirling star in Hollington Drive and Ben Aldridge plays the lead in The Long Call, adapted from Ann Cleeves' novel of the same title.
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