The famed museum said it was removing the band's figures from display to keep up with the 'ever-changing' world of showbiz.
In a statement a spokesperson said: "Following One Direction's 10th anniversary earlier this summer, the decision has been made to remove Harry, Liam, Zayn, Louis and Niall's figures from the attraction floor at Madame Tussauds London.
"The figures have been an important part of the attraction since their launch in 2013 and we know fans have loved having the chance to 'meet' the band.
"With each member of the band's continuing success in their solo careers we felt this anniversary was a fitting moment for the figures to bow out and end their tenure at the attraction as a five-piece."
Revealing the reasoning behind scrapping the waxworks, Madame Tussauds wrote: "We are constantly updating what guests can expect to see at Madame Tussauds London, reacting to the celebrity landscape.
"The showbiz world is ever-changing, and so are we.
"Much like One Direction's dedicated fan base, we're keenly watching what the gentlemen have up their sleeves for the next decade."
The news didn't go down well with everyone and some die-hard fans got pretty angry over the removal.
Meanwhile others were even offering to buy the waxworks from the attraction to save them from being melted down.
One fuming fan wrote on Twitter: "But you still have The Beatles one up when that band died like 50 years ago but you remove One Direction bc they went on hiatus 5 years ago.
"Can't you like leave it there for like... forever? just get lost all of you Madame Tussauds [sic]."
Another wrote: "Never got to see them live and now I won't be able to see them as wax figures."
While an optimist wrote: "OK, send them to me?"
Good luck with that one, mate.
One Direction went on hiatus in 2015, ostensibly for 18 months, but have yet to confirm when or if they will return.
This isn't the first time Madame Tussauds has caused a stir with its waxworks this year.
Back in January the attraction announced it was moving Prince Harry and wife Meghan from the rest of the Royal Family set after they announced they'd be taking a step back from Royal duties.