The singer's picture became the photo to reach one million likes the fastest, reaching that milestone in just under six minutes.
As it stands, the photo has almost 16 million likes.
The cover was an idea of Billie's own devising and shows her wearing 1940s pin-up style clothing with blonde hair, which is quite a departure from the look her fans have become used to over the years.
Speaking about the shoot, Eilish - who said the style was her own idea - said: "I love these pictures and I loved doing this shoot.
"Do whatever you want whenever you want. F*** everything else."
Sound enough advice when it comes to this sort of thing.
Eilish previously broke the Instagram record back in March when she revealed she'd dyed her hair blonde, and that picture went on to become the third most liked photograph on the site, racking up more than 22.8 million likes.
Another photograph of the singer, this time wearing a trench coat and a corset, is the fourth most-liked photos of all time, receiving 20.9 million likes at the time of writing.
It's almost certain to grow, too.
Outside of that other photo of Eilish, it's only behind the last ever post made by XXXTentacion before he died and that photo of an egg.
The internet can be a strange place at times, can't it?
On her decision to adopt a different style to her famous baggy clothes, Eilish said: "[People might say] If you're about body positivity, why would you wear a corset? Why wouldn't you show your actual body?
"My thing is I can do whatever I want.
"Showing your body and showing your skin, or not, should not take any respect away from you."
The 19-year-old recently shared the third single from her forthcoming album 'Happier Than Ever'.
New track 'Your Power' discusses abuses of power by older men, a theme that Eilish has covered before.
She described the song as 'an open letter to people who take advantage - mostly men' and said she hoped people would actually listen to the music rather than trying to figure out who she is talking about.
Eilish added: "I would like people to listen to me, and not just try to figure out who I'm talking about, because it's not about that.
"It's really not at all about one person. You might think, 'It's because she's in the music industry' - no, dude. It's everywhere.
"I don't know one girl or woman who hasn't had a weird experience, or a really bad experience. And men, too - young boys are taken advantage of constantly."
Featured Image Credit: Vogue/Craig McDean